Document Detail


Nanomechanical identification of proteins using microcantilever-based chemical sensors.
MedLine Citation:
PMID:  23034564     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We have developed a microcantilever based sensor array which can be functionalized with mercapto-compounds to detect proteins. Linear discriminant analysis (LDA) is used to differentiate the cantilever deflection patterns. It is concluded that more sensors give better separating capacity and the COOH and Si-OCH(3) groups are important factors in protein recognition.
Authors:
Ping Wang; Hao Pei; Ying Wan; Jiang Li; Xinhua Zhu; Yan Su; Chunhai Fan; Qing Huang
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-4
Journal Detail:
Title:  Nanoscale     Volume:  -     ISSN:  2040-3372     ISO Abbreviation:  Nanoscale     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101525249     Medline TA:  Nanoscale     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China. huangqing@sinap.ac.cn.
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