Document Detail

Naloxone suppresses insulin-induced food intake in novel and familiar environments, but does not affect hypoglycemia.
MedLine Citation:
PMID:  7051049     Owner:  NLM     Status:  MEDLINE    
The opiate antagonist naloxone reduced the food intake induced in rats by acute injection of insulin. The suppression was most marked in the first hour after insulin injection. Insulin provoked less food intake when rats were tested in a novel environment compared with those tested in their home cage, but naloxone again significantly suppressed the intake in the first hour. Naloxone had no effect upon insulin-induced hypoglycemia.
N Rowland; T J Bartness
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  16     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:  1982 Jun 
Date Detail:
Created Date:  1982-10-12     Completed Date:  1982-10-12     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1001-3     Citation Subset:  IM    
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MeSH Terms
Blood Glucose / metabolism*
Eating / drug effects*
Insulin / pharmacology*
Naloxone / pharmacology*
Social Environment*
Reg. No./Substance:
0/Blood Glucose; 11061-68-0/Insulin; 465-65-6/Naloxone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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