| Naloxone in chronic schizophrenic patients: neuroendocrine and behavioral effects. | |
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MedLine Citation:
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PMID: 6127744 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Naloxone produced improvement in abnormal thought content in medicated chronic schizophrenic patients, but not in drug-free patients. In contrast, drowsiness and increases in plasma prolactin concentrations were seen only in drug-free schizophrenic patients. Although growth hormone concentrations increased in drug-free and medicated schizophrenic patients, the time course was different in the two groups. Neuroleptics appear to alter naloxone's clinical and neuroendocrine effects in chronic schizophrenic patients. |
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Authors:
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J E Kleinman; D R Weinberger; A Rogol; D J Shiling; W B Mendelson; G C Davis; W E Bunney; R J Wyatt |
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Publication Detail:
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Type: Clinical Trial; Journal Article |
Journal Detail:
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Title: Psychiatry research Volume: 7 ISSN: 0165-1781 ISO Abbreviation: Psychiatry Res Publication Date: 1982 Aug |
Date Detail:
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Created Date: 1982-12-18 Completed Date: 1982-12-18 Revised Date: 2008-04-17 |
Medline Journal Info:
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Nlm Unique ID: 7911385 Medline TA: Psychiatry Res Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 1-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antipsychotic Agents / therapeutic use Chronic Disease Clinical Trials as Topic Double-Blind Method Female Growth Hormone / blood* Humans Infusions, Parenteral Male Middle Aged Naloxone / therapeutic use* Prolactin / blood* Psychiatric Status Rating Scales Schizophrenia / blood, drug therapy* Schizophrenic Psychology* |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 465-65-6/Naloxone; 9002-62-4/Prolactin; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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