Document Detail


Is nail fold capillaroscopy useful in normotensive and primary open angle glaucoma? A pilot study.
MedLine Citation:
PMID:  20929293     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Purpose: Vascular dysregulation is deemed a significant risk factor in glaucoma occurrence and progression. Capillaroscopy of the blood vessels on the finger nail-fold is a method that can provide information regarding the state of the vascular system at the capillary level. The aim of this pilot study was to determine whether there are significant differences in the morphological characteristics of the peripheral blood vessels in normotensive glaucoma and primary open angle glaucoma. Matherials and Methods: An ophthalmological and capillaroscopic examination was conducted on 30 normotensive glaucoma patients and 30 primary open angle glaucoma patients. The capillaroscopic characteristics described were as follows: capillary row density, capillary diameter, number of spirally formed capillaries, permeability of the loop, and loop resistance. Results: Statistically, significantly more intensively spiraled capillaries were found in normotensive glaucoma patients (χ(2) test, p < 0.05). Conclusions: Results confirm the thesis that vascular factors play a significant role in the pathogenesis of the glaucoma, especially in cases where the level of intraocular pressure cannot be deemed responsible for the present damage of the optical nerve. Despite the newer, technologically more developed methods for diagnostics and monitoring glaucoma, it is often not easy to establish the right diagnosis and determine further the course of the illness, since the role the intraocular pressure (IOP) plays compared to the role of vascular factors is unknown; hence, capillaroscopy as a complementary diagnostic procedure can be of help.
Authors:
Marija Božić; Paraskeva-Hentova Senćanić; Goran Spahić; Dorđe Kontić; Vujica Marković; Ivan Marjanović; Milenko Stojkovic; Jasmina Dorđević-Jocić
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Publication Detail:
Type:  Journal Article     Date:  2010-10-07
Journal Detail:
Title:  Current eye research     Volume:  35     ISSN:  1460-2202     ISO Abbreviation:  Curr. Eye Res.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-12-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8104312     Medline TA:  Curr Eye Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  1099-104     Citation Subset:  IM    
Affiliation:
Institute for Eye Diseases, Clinical Center of Serbia, Belgrade, Serbia.
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