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Na, Cl, and water transport by rat ileum in vitro.
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MedLine Citation:
PMID:  13813357     Owner:  NLM     Status:  MEDLINE    
Interrelationships between metabolism, NaCl transport, and water transport have been studied in an in vitro preparation of rat ileum. When glucose is present in the mucosal solution, Na and Cl both appear to be actively transported from mucosa to serosa while water absorption is passive and dependent on net solute transport. Removal of glucose from the mucosal solution or treatment with dinitrophenol, monoiodoacetate, or anoxia inhibits active salt transport and as a result, water absorption is also inhibited. The dependence of water absorption on metabolism can be explained as a secondary effect due to its dependence on active salt transport. The relationship between salt and water transport has been discussed in terms of a model system.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of general physiology     Volume:  43     ISSN:  0022-1295     ISO Abbreviation:  J. Gen. Physiol.     Publication Date:  1960 Jul 
Date Detail:
Created Date:  1960-12-01     Completed Date:  1998-11-01     Revised Date:  2010-09-20    
Medline Journal Info:
Nlm Unique ID:  2985110R     Medline TA:  J Gen Physiol     Country:  Not Available    
Other Details:
Languages:  eng     Pagination:  1137-48     Citation Subset:  OM    
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MeSH Terms
Ileum / physiology*
Sodium Chloride / metabolism*
Water / metabolism*
Reg. No./Substance:
7647-14-5/Sodium Chloride; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Full Text
Journal Information
Journal ID (nlm-ta): J Gen Physiol
ISSN: 0022-1295
ISSN: 1540-7748
Publisher: The Rockefeller University Press
Article Information
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Copyright © Copyright, 1960, by The Rockefeller Institute
Received Day: 25 Month: 11 Year: 1959
Print publication date: Day: 1 Month: 7 Year: 1960
Volume: 43 Issue: 6
First Page: 1137 Last Page: 1148
ID: 2195073
PubMed Id: 13813357

Na, Cl, and Water Transport by Rat Ileum in Vitro
Peter F. Curran
From the Biophysical Laboratory, Harvard Medical School, Boston, Massachusetts, and the Institute for Biological Chemistry, the University of Copenhagen, Copenhagen, Denmark.
Dr. Curran's present address is the Biophysical Laboratory, Harvard Medical School, Boston.

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