| NSAIDs and the gastrointestinal tract: an update on recent progress. | |
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MedLine Citation:
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PMID: 10732398 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This article outlines the mechanisms involved in specific cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) inhibition as they relate to the safety of nonsteroidal anti-inflammatory drug (NSAID) use. New advancements in COX-2 technology appear to improve the safety profile of NSAID therapy. Gastroenterologic issues such as ulcer disease and liver disease as related to these novel new medications are reviewed. |
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Authors:
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G J Silverman |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Journal of the American Osteopathic Association Volume: 99 ISSN: 0098-6151 ISO Abbreviation: J Am Osteopath Assoc Publication Date: 1999 Aug |
Date Detail:
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Created Date: 2000-04-21 Completed Date: 2000-04-21 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7503065 Medline TA: J Am Osteopath Assoc Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: S10-3 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Anti-Inflammatory Agents, Non-Steroidal*
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adverse effects,
therapeutic use Arthritis / drug therapy Cyclooxygenase Inhibitors* / therapeutic use Digestive System / drug effects Humans Liver / drug effects Safety |
| Chemical | |
Reg. No./Substance:
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0/Anti-Inflammatory Agents, Non-Steroidal; 0/Cyclooxygenase Inhibitors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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