Document Detail

NOR associations with heterochromatin.
MedLine Citation:
PMID:  6488898     Owner:  NLM     Status:  MEDLINE    
Associations between nucleolus organizer regions (NORs) and non-acrocentric chromosomes were scored in 2,800 metaphase spreads from PHA-stimulated lymphocyte cultures (48 h) from 14 individuals. The preparations were both silver stained and C-banded. In order to calculate the expected values for associations, the ratio of heterochromatin length to euchromatin length was established for each subject. Individual C-band lengths and centromeric lengths were also determined. When silver connective (SC) associations with heterochromatin were compared to SC associations with euchromatin, the number of associations with heterochromatin was significantly greater than expected (P less than 0.000001) for each subject. The SC associations were not distributed randomly over the heterochromatin of the non-acrocentrics. Chromosomes 1 and 2 had significantly more than expected. Chromosomes 17, 18, 19, 20, and the Y had fewer than expected. NOR associations with euchromatic segments also showed a nonrandom pattern of distribution.
C M Tuck-Muller; B L Bordson; M Varela; J W Bennett
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cytogenetics and cell genetics     Volume:  38     ISSN:  0301-0171     ISO Abbreviation:  Cytogenet. Cell Genet.     Publication Date:  1984  
Date Detail:
Created Date:  1984-11-28     Completed Date:  1984-11-28     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0367735     Medline TA:  Cytogenet Cell Genet     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  165-70     Citation Subset:  IM    
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MeSH Terms
Chromosome Banding / methods
Chromosomes, Human, 1-3 / ultrastructure
Chromosomes, Human, 16-18 / ultrastructure
Chromosomes, Human, 6-12 and X / ultrastructure
Heterochromatin / ultrastructure*
Nucleolus Organizer Region / ultrastructure*
Y Chromosome / ultrastructure
Reg. No./Substance:

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