| NOR associations with heterochromatin. | |
MedLine Citation:
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PMID: 6488898 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Associations between nucleolus organizer regions (NORs) and non-acrocentric chromosomes were scored in 2,800 metaphase spreads from PHA-stimulated lymphocyte cultures (48 h) from 14 individuals. The preparations were both silver stained and C-banded. In order to calculate the expected values for associations, the ratio of heterochromatin length to euchromatin length was established for each subject. Individual C-band lengths and centromeric lengths were also determined. When silver connective (SC) associations with heterochromatin were compared to SC associations with euchromatin, the number of associations with heterochromatin was significantly greater than expected (P less than 0.000001) for each subject. The SC associations were not distributed randomly over the heterochromatin of the non-acrocentrics. Chromosomes 1 and 2 had significantly more than expected. Chromosomes 17, 18, 19, 20, and the Y had fewer than expected. NOR associations with euchromatic segments also showed a nonrandom pattern of distribution. |
Authors:
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C M Tuck-Muller; B L Bordson; M Varela; J W Bennett |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cytogenetics and cell genetics Volume: 38 ISSN: 0301-0171 ISO Abbreviation: Cytogenet. Cell Genet. Publication Date: 1984 |
Date Detail:
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Created Date: 1984-11-28 Completed Date: 1984-11-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0367735 Medline TA: Cytogenet Cell Genet Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 165-70 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromosome Banding
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methods Chromosomes, Human, 1-3 / ultrastructure Chromosomes, Human, 16-18 / ultrastructure Chromosomes, Human, 6-12 and X / ultrastructure Female Heterochromatin / ultrastructure* Humans Karyotyping Male Metaphase Nucleolus Organizer Region / ultrastructure* Y Chromosome / ultrastructure |
| Chemical | |
Reg. No./Substance:
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0/Heterochromatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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