Document Detail


NMR probe for pressure-jump experiments up to 250 bars and 3 ms jump time.
MedLine Citation:
PMID:  21034114     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
We describe the design and performance of a pressure-jump instrument for time-resolved NMR experiments. Initial pressure of up to 250 bars can be produced by means of a HPLC pump and distilled water as a pressure-transmitting liquid. Fast pressure release at a time resolution of 3 ms is achieved using a fast acting valve driven by a piezostack close to the sample chamber. The pressure-jump cell is placed together with two valves in an especially designed NMR probe, which can be used in standard spectrometers with wide-bore magnets. All functions of the instrument are personal computer controlled. The equipment is designed for investigations on systems of biological interest, especially lipid-water dispersions. A theoretical consideration implies that probably the limited speed of valve opening determines the lower boundary of the jump time. The performance is illustrated by time-resolved NMR spectra across the phase transition of a phospholipid-water dispersion after a pressure jump from 100 bars to atmospheric pressure.
Authors:
U Heuert; M Krumova; G Hempel; M Schiewek; A Blume
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Review of scientific instruments     Volume:  81     ISSN:  1089-7623     ISO Abbreviation:  Rev Sci Instrum     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-11-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0405571     Medline TA:  Rev Sci Instrum     Country:  United States    
Other Details:
Languages:  eng     Pagination:  105102     Citation Subset:  IM    
Affiliation:
Insitut für Physik, Martin-Luther University Halle-Wittenberg, Betty-Heimann-Str. 7, D-06120 Halle/Saale, Germany.
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