Document Detail


NIRS study of cerebral oxygenation and hemodynamics in neonate at birth.
MedLine Citation:
PMID:  22254538     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To study the changes of cerebral oxygenation and hemodynamics in normal neonates at 2-5 min post-birth and understand the effects of pregnancy-induced hypertension (PIH) upon cerebral oxygenation and hemodynamics in newborn neonates. The near infrared spectroscopy (NIRS) was employed to measure the absolute quantity of brain tissue oxygen saturation (rSO2) in newborn neonates and the changes of concentrations of deoxyhemoglobin (Hb) and oxygenation hemoglobin (HbO2) with time relative to initial values to further obtain the changes of total hemoglobin (tHb) and cerebral perfusion (denoted by HbD). In normal neonates at 2-5 min post-birth, rSO2 increased while tHb remained relatively stable and HbD increased. In neonates born of PIH mothers at 3-5 min post-birth, the changes of tHb were markedly higher than those in the normal infants, p<0.05; at 2-5 min post-birth, the changes were markedly lower than the normal term infants. We concluded that NIRS can detect the changes of cerebral oxygenation and blood flow in a non-invasive and effective way.
Authors:
Xinlin Hou; Haiyan Ding; Yichao Teng; Congle Zhou; Dandan Zhang
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  2011     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2011  
Date Detail:
Created Date:  2012-01-18     Completed Date:  2012-06-12     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1229-32     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity / physiology
Brain / physiology*
Cerebrovascular Circulation / physiology*
Female
Humans
Infant, Newborn
Male
Oximetry / methods*
Oxygen / analysis*
Reproducibility of Results
Rheology / methods*
Sensitivity and Specificity
Spectroscopy, Near-Infrared / methods*
Chemical
Reg. No./Substance:
S88TT14065/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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