Document Detail

NAVA ventilation.
MedLine Citation:
PMID:  20395897     Owner:  NLM     Status:  MEDLINE    
Neurally adjusted ventilatory assist (NAVA) is a form of partial ventilatory support wherein the machine applies positive pressure to the airway opening throughout each inspiration. In contrast to all other modes of ventilation, which adopt conventional pneumatic signals (flow, volume, and airway pressure) to drive and control the ventilator operation, NAVA utilizes the electrical activity of the diaphragm, which is the best available signal to estimate the respiratory drive and to trigger on and cycle off the delivery of the mechanical assistance and regulate its amount and intra-breath profile. With NAVA, therefore, the patient retains full control of the breathing pattern. Following the first description of NAVA ten years ago, various studies have been performed on this mode of ventilation, either in animal models, healthy subjects, or in adult and pediatric critically ill patients. These investigations indicate that this novel mode is efficient in unloading the respiratory muscles and maintaining adequate gas exchange while improving the patient-ventilator interaction. This review article aims to summarize the results of the studies published to date on this topic.
P Navalesi; D Colombo; F Della Corte
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Minerva anestesiologica     Volume:  76     ISSN:  1827-1596     ISO Abbreviation:  Minerva Anestesiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-16     Completed Date:  2010-07-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375272     Medline TA:  Minerva Anestesiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  346-52     Citation Subset:  IM    
Unit of Anesthesiology and Intensive Care, Department of Clinical and Experimental Medicine, A. Avogadro University, Maggiore della Carità University Hospital, Novara, Italy.
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MeSH Terms
Carbon Dioxide / blood
Intensive Care
Life Support Systems
Randomized Controlled Trials as Topic
Respiration, Artificial*
Respiratory Mechanics / physiology
Reg. No./Substance:
124-38-9/Carbon Dioxide

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