Document Detail


NADPH oxidase in the kidney: a Janus in determining cell fate.
MedLine Citation:
PMID:  19116641     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
NADPH oxidase-derived reactive oxygen species are implicated in apoptosis in certain kidney cells. On the other hand, NADPH oxidase is also involved in promoting cell proliferation in the kidney. The two faces of NADPH oxidase in these situations prompt us to argue that the role of this enzyme in various kidney diseases needs to be addressed in a cell-specific manner.
Authors:
Fan Jiang
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Kidney international     Volume:  75     ISSN:  1523-1755     ISO Abbreviation:  Kidney Int.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-31     Completed Date:  2009-02-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0323470     Medline TA:  Kidney Int     Country:  United States    
Other Details:
Languages:  eng     Pagination:  135-7     Citation Subset:  IM    
Affiliation:
Bernard O'Brien Institute of Microsurgery, University of Melbourne, Melbourne, Victoria, Australia. fjiang@unimelb.edu.au
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MeSH Terms
Descriptor/Qualifier:
Apoptosis
Cell Proliferation
Humans
Hypertrophy
Kidney / cytology,  enzymology*,  pathology*
NADPH Oxidase / physiology*
Reactive Oxygen Species
Chemical
Reg. No./Substance:
0/Reactive Oxygen Species; EC 1.6.3.1/NADPH Oxidase
Comments/Corrections
Comment On:
Kidney Int. 2009 Jan;75(2):156-66   [PMID:  18923387 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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