Document Detail


N-sulfonylbenzotriazoles as advantageous reagents for C-sulfonylation.
MedLine Citation:
PMID:  16268589     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
[Structure: see text]. Reactions of readily available N-(alkyl-, aryl-, and heteroarylsulfonyl)benzotriazoles 3a-h with diverse nitriles, reactive heteroaromatics, alkylheteroaromatics, sulfones, and esters produced alpha-cyanoalkyl sulfones 5a-i, sulfonylheteroaromatics 7a-e, alpha-(sulfonylalkyl)heterocycles 9a-f, alpha-sulfonylalkyl sulfones 11a-g, and esters of alpha-sulfonyl acids 14a-c, respectively, in synthetically useful to excellent yields. The results represent the first examples of the successful application of sulfonylazoles for C-sulfonylation.
Authors:
Alan R Katritzky; Ashraf A A Abdel-Fattah; Anatoliy V Vakulenko; Hui Tao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  70     ISSN:  0022-3263     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-11-04     Completed Date:  2006-06-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  9191-7     Citation Subset:  IM    
Affiliation:
Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville, Florida 32611-7200, USA. katritzky@chem.ufl.edu
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MeSH Terms
Descriptor/Qualifier:
Sulfones / chemical synthesis*,  chemistry*
Sulfonic Acids / chemistry*
Triazoles / chemical synthesis,  chemistry*
Chemical
Reg. No./Substance:
0/Sulfones; 0/Sulfonic Acids; 0/Triazoles

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