Document Detail

N-phenylglycolhydroxamate production by the action of transketolase on nitrosobenzene.
MedLine Citation:
PMID:  921749     Owner:  NLM     Status:  MEDLINE    
The incubation of nitrosobenzene with yeast transketolase and D-xylulose 5-phosphate resulted in the production of N-phenylglycolhydroxamic acid. The addition of D-ribose 5-phosphate decreased the amount of hydroxamic acid that was produced. This conversion of nitrosobenzene into the glycollic acid-derived hydroxamic acid was shown to be an enzymic process, and a chemical mechanism for the conversion was proposed.
M D Corbett; B R Chipko
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Biochemical journal     Volume:  165     ISSN:  0264-6021     ISO Abbreviation:  Biochem. J.     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2984726R     Medline TA:  Biochem J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  263-7     Citation Subset:  IM    
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MeSH Terms
Hydroxamic Acids / biosynthesis*
Nitroso Compounds / metabolism*
Ribosemonophosphates / pharmacology
Transketolase / metabolism*
Reg. No./Substance:
0/Hydroxamic Acids; 0/Nitroso Compounds; 0/Pentosephosphates; 0/Ribosemonophosphates; EC

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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