Document Detail


N -Methyl-D-Aspartate (NMDA)-Mediated Excitotoxic Damage: A Mouse Model of Acute Retinal Ganglion Cell Damage.
MedLine Citation:
PMID:  23150363     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The animal model of N-methyl-D-aspartate (NMDA)-induced excitotoxic damage of retinal ganglion cells (RGC) is widely used to study the molecular mechanisms of RGC apoptosis and/or its prevention by neuroprotective agents. This chapter provides protocols for applying NMDA-induced excitotoxic damage to RGC of mouse eyes and for subsequent measuring of the extent of the resulting damage.
Authors:
Roswitha Seitz; Ernst R Tamm
Related Documents :
24676493 - The role of oxytocin in cardiovascular regulation.
24411493 - Lymphotoxin organizes contributions to host defense and metabolic illness from innate l...
20943043 - Benzene metabolites inhibit the release of proinflammatory mediators and cytokines from...
Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Methods in molecular biology (Clifton, N.J.)     Volume:  935     ISSN:  1940-6029     ISO Abbreviation:  Methods Mol. Biol.     Publication Date:  2013  
Date Detail:
Created Date:  2012-11-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9214969     Medline TA:  Methods Mol Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  99-109     Citation Subset:  -    
Affiliation:
Institute for Human Anatomy and Embryology, University of Regensburg, Regensburg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Light Damage as a Model of Retinal Degeneration.
Next Document:  Generation of Transgenic X. laevis Models of Retinal Degeneration.