| A Mystery Wrapped in an Enigma: Matrigel Enhancement of Mammary Cell Growth and Morphogenesis. | |
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MedLine Citation:
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PMID: 22581302 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The analysis of normal mammary morphogenesis is facilitated by the use of mammary fat pad transplantation. The recent experiments on analysis of normal mammary epithelial stem cell activity rely heavily on this technique. In this review, we discuss the known and unknown attributes of using Matrigel in the injection of the mammary epithelial cell suspension. Matrigel greatly increases the "take" frequency of the injected cell suspension; however, there is some uncertainty regarding the interpretation of some of the results. After consideration of these issues, our conclusion is that Matrigel is important in order to obtain rigorous and reproducible results. |
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Authors:
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Michael T Lewis; John D Landua; Homer C Adams; Daniel Medina |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-13 |
Journal Detail:
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Title: Journal of mammary gland biology and neoplasia Volume: - ISSN: 1573-7039 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9601804 Medline TA: J Mammary Gland Biol Neoplasia Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Lester and Sue Smith Breast Center, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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