Document Detail

Myotonic dystrophies and the heart.
MedLine Citation:
PMID:  22143278     Owner:  NLM     Status:  In-Data-Review    
Myotonic dystrophy (MD) is a neuromuscular disorder of autosomal dominant inheritance, which is categorized by 2 main sub-types: type 1 (MD1) and type 2 (MD2). This disease is characterized by myotonia and various multisytemic complications, most commonly of the cardiac, endocrine, and central nervous systems. In addition, cardiac abnormalities contribute to a significant morbidity and mortality in these patients. The cardiac abnormalities common to MD1 are conduction defects, such as first-degree atrioventricular block, arrhythmias, and other less common manifestations such as heart failure, ischemic heart disease, and mitral valve prolapse. Although these cardiac manifestations are also common in MD2, another complication that has been linked to MD2 is cardiomyopathy. Further study needs to be performed to better understand the pathology and management of these cardiac disorders associated with MD.
Sunit-Preet Chaudhry; William H Frishman
Related Documents :
10029898 - Subcellular distribution of prostaglandin-e2 and prostaglandin-f2 alpha in atrial tissu...
17954068 - Atrial function after ablation procedure in patients with chronic atrial fibrillation u...
15216028 - Suprasternal notch echocardiography and atrial arrhythmias.
9647098 - Right atrial isolation for atrial fibrillation associated with atrial septal defect.
15904648 - Association of height with outcomes in patients with acute myocardial infarction receiv...
1697958 - A technique for intraoperative arrhythmia induction during automatic implantable defibr...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiology in review     Volume:  20     ISSN:  1538-4683     ISO Abbreviation:  Cardiol Rev     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2011-12-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304686     Medline TA:  Cardiol Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1-3     Citation Subset:  IM    
*Department of Medicine, Case Western Reserve University Hospital, Cleveland, OH †Department of Medicine, New York Medical College/Westchester Medical Center, Valhalla, NY.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Lack of association between objectively assessed sleep disorders and inflammatory markers among kidn...
Next Document:  Vascular ehlers-danlos syndrome: pathophysiology, diagnosis, and prevention and treatment of its co...