Document Detail

Myospherulosis of the oral hard and soft tissues.
MedLine Citation:
PMID:  6371201     Owner:  NLM     Status:  MEDLINE    
Myospherulosis is a unique, inflammatory, granulomatous lesion, which results from the action of lipid substances on extravasated erythrocytes. Petrolatum-based antibiotic ointments are the most frequent etiologic agents of iatrogenically acquired lesions. Six intraoral cases of myospherulosis are presented, including the first reported case in oral soft tissues. The literature of reported cases is summarized and the epidemiology, histopathology, and ultrastructure of the lesions are discussed. Predisposing events and recommendations for future use of petrolatum-based antibiotic ointments are presented.
D P Lynch; J R Newland; J L McClendon
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons     Volume:  42     ISSN:  0278-2391     ISO Abbreviation:  J. Oral Maxillofac. Surg.     Publication Date:  1984 Jun 
Date Detail:
Created Date:  1984-06-21     Completed Date:  1984-06-21     Revised Date:  2009-10-06    
Medline Journal Info:
Nlm Unique ID:  8206428     Medline TA:  J Oral Maxillofac Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  349-55     Citation Subset:  AIM; D; IM    
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MeSH Terms
Administration, Topical*
Anti-Inflammatory Agents / administration & dosage
Drug Combinations / administration & dosage
Erythrocytes, Abnormal / pathology*
Foreign-Body Reaction / etiology,  pathology*
Gingival Diseases / etiology,  pathology*
Mandibular Diseases / etiology,  pathology*
Ointment Bases / adverse effects
Oxytetracycline / administration & dosage
Petrolatum / adverse effects
Spherocytes / pathology*
Reg. No./Substance:
0/Anti-Inflammatory Agents; 0/Drug Combinations; 0/Ointment Bases; 50-23-7/Hydrocortisone; 79-57-2/Oxytetracycline; 8009-03-8/Petrolatum

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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