Document Detail


Myopathic dropped head syndrome: a syndrome of mixed aetiology.
MedLine Citation:
PMID:  10938615     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report two patients with myopathic dropped head syndrome, a rare and interesting neuromuscular syndrome characterised by a predominant weakness of the neck extensor muscles. The first patient, a middle aged Chinese man, presented with progressive weakness of neck extension but his clinical course later stabilised despite a lack of response to corticosteroids. Muscle biopsy revealed a necrotising myopathy with no evidence of inflammation. This patient supports the existence of an idiopathic restricted non-inflammatory myopathy, a so called isolated neck extensor myopathy syndrome which is recognised to pursue a less progressive, more benign course. Our second patient had histopathological evidence for polymyositis; there was a favourable response to steroids. Our cases underscore the fact that there may be a spectrum of pathological processes associated with the myopathic dropped head syndrome ranging from non-inflammatory muscle necrosis to a full blown inflammatory myositis.
Authors:
K J Goh; K T Wong; C T Tan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia     Volume:  7     ISSN:  0967-5868     ISO Abbreviation:  J Clin Neurosci     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-09-14     Completed Date:  2000-09-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9433352     Medline TA:  J Clin Neurosci     Country:  SCOTLAND    
Other Details:
Languages:  eng     Pagination:  334-6     Citation Subset:  IM    
Copyright Information:
Copyright 2000 Harcourt Publishers Ltd.
Affiliation:
Division of Neurology, Department of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
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MeSH Terms
Descriptor/Qualifier:
Adult
Head Movements / physiology
Humans
Male
Middle Aged
Muscle Weakness / etiology*,  pathology*,  physiopathology
Muscular Diseases / complications*,  pathology*,  physiopathology
Neck Muscles / pathology*,  physiopathology

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