Document Detail

Myometrial invasion of endometrial carcinoma: assessment with dynamic MR and contrast-enhanced T1-weighted images.
MedLine Citation:
PMID:  9022575     Owner:  NLM     Status:  MEDLINE    
AIM: To evaluate the usefulness of dynamic magnetic resonance (MR) imaging in assessing the depth of myometrial invasion, compared with conventional T2-weighted and contrast-enhanced T1-weighted imaging. PATIENTS AND METHODS: Forty patients with endometrial carcinoma were examined with T2-weighted images, dynamic studies and contrast-enhanced T1-weighted images, preoperatively. We evaluated enhancement patterns of myometrium and tumour, and compared MR findings with histological results concerning the depth of myometrial invasion. RESULTS: In assessing the depth of myometrial invasion, the accuracy of T2-weighted images, dynamic studies and contrast-enhanced T1-weighted images was 58%, 85% and 68%, respectively. The tumour-myometrial contrast of dynamic studies was higher than that of other images. In addition, subendometrial enhancement (SEE) was frequently observed in dynamic studies in post-menopausal women, which was an important landmark in detecting myometrial invasion. CONCLUSION: We consider that dynamic MR imaging has greater advantage in assessing myometrial invasion than T2-weighted or contrast-enhanced T1-weighted imaging.
H Seki; M Kimura; K Sakai
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Clinical radiology     Volume:  52     ISSN:  0009-9260     ISO Abbreviation:  Clin Radiol     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-03-04     Completed Date:  1997-03-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  1306016     Medline TA:  Clin Radiol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  18-23     Citation Subset:  IM    
Department of Radiology, Niigata University School of Medicine, Japan.
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MeSH Terms
Contrast Media
Diagnostic Errors
Drug Combinations
Endometrial Neoplasms / pathology*
Gadolinium / diagnostic use
Gadolinium DTPA
Magnetic Resonance Imaging / methods*
Meglumine / diagnostic use
Middle Aged
Myometrium / pathology*
Neoplasm Invasiveness
Organometallic Compounds / diagnostic use
Pentetic Acid / analogs & derivatives,  diagnostic use
Predictive Value of Tests
Prospective Studies
Sensitivity and Specificity
Reg. No./Substance:
0/Contrast Media; 0/Drug Combinations; 0/Organometallic Compounds; 6284-40-8/Meglumine; 67-43-6/Pentetic Acid; 7440-54-2/Gadolinium; 80529-93-7/Gadolinium DTPA

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