Document Detail

Myometrial cystic formation after local methotrexate application into cornual gestational sac: a case report of an unexpected complication.
MedLine Citation:
PMID:  22567513     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Cornual pregnancy is a rare type of ectopic pregnancy, and diverse therapeutic options exist for the management. Medical treatment despite high initial beta HCG values is not thought to be safe. We reported a 39-year-old woman with an initial beta HCG value of 22000 mIU/mL and diagnosed of a cornual pregnancy. Patient was managed successfully with the administration of combined systemic and ultrasonographically guided local injection of methotrexate into the gestational sac. During followup with serial beta hcg measurements, 27 × 20 mm cystic area in myometrium has been detected. Beta hcg <1 mIU/mL value was reached three months later, and this cystic area resolved spontaneously. Systemic methotrexate administration combined with ultrasound-guided local methotrexate injection into the gestational sac might be considered as the first-line treatment in the management of hemodynamically stable patients having cornual pregnancy even with high beta HCG values and risk of myometrial cystic formation.
Zehra Sema Ozkan; Banu Kumbak; Ekrem Sapmaz; Mehmet Simsek
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Publication Detail:
Type:  Journal Article     Date:  2011-07-09
Journal Detail:
Title:  Case reports in obstetrics and gynecology     Volume:  2011     ISSN:  2090-6692     ISO Abbreviation:  Case Rep Obstet Gynecol     Publication Date:  2011  
Date Detail:
Created Date:  2012-05-08     Completed Date:  2012-08-23     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  101576454     Medline TA:  Case Rep Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  619094     Citation Subset:  -    
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