Document Detail

Myomectomy: a retrospective study to examine reproductive performance before and after surgery.
MedLine Citation:
PMID:  10402378     Owner:  NLM     Status:  MEDLINE    
The aim of this retrospective study was to establish the impact of myomectomy on pregnancy outcome with particular reference to its effect on the incidence of pregnancy loss. Myomectomy was performed using microsurgical procedures upon 51 women who had intramural or subserosal fibroids and wished to conceive. Overall, the conception rate following myomectomy was 57%. Multiple regression analysis showed that age was the only factor which influenced conception rate: </=35 years, 74% (23/31); >/=36 years, 30% (6/20; P < 0.005). The pregnancy loss rate prior to myomectomy was 60% (24/40), which was reduced to 24% (8/33) after myomectomy (P < 0.001). There was no instance of premature labour or scar rupture among 25 live births. This retrospective study suggests that myomectomy for intramural and subserosal fibroids may significantly improve the reproductive performance of women presenting with infertility or pregnancy loss.
T C Li; R Mortimer; I D Cooke
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  14     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1999 Jul 
Date Detail:
Created Date:  1999-09-13     Completed Date:  1999-09-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1735-40     Citation Subset:  IM    
Jessop Hospital for Women, Leavygreave Road, Sheffield S3 7RE, UK.
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MeSH Terms
Abortion, Spontaneous / etiology,  prevention & control
Gynecologic Surgical Procedures*
Infant, Newborn
Infertility, Female / etiology,  surgery
Leiomyoma / complications,  surgery*
Myometrium / surgery*
Pregnancy Complications, Neoplastic
Pregnancy Outcome
Retrospective Studies
Uterine Neoplasms / complications,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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