| Myocarditis and pulmonary arteritis in mice associated with the presence of rickettsia-like bodies in polymorphonuclear leucocytes. | |
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MedLine Citation:
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PMID: 13109116 Owner: NLM Status: OLDMEDLINE |
Abstract/OtherAbstract:
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A previously undescribed disease of mice, characterized by acute interstitial myocarditis, and by periarterial pulmonary lesions, is reported. The transmissibility of this disease has been shown, but a large proportion of inoculated mice appears to be resistant. Microorganisms, rickettsial in form but not positively identified as such, are consistently present in the lesions. They are found predominantly in the cytoplasm of polymorphonuclear leucocytes. Filtrates of fecal material from normal mice of the Harvard breeding stock may produce lesions in myocardium and pulmonary arteries indistinguishable from those occurring in this disease. Rickettsia-like bodies are also found in these lesions. |
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Authors:
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A M PAPPENHEIMER; J B DANIELS |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of experimental medicine Volume: 98 ISSN: 0022-1007 ISO Abbreviation: J. Exp. Med. Publication Date: 1953 Dec |
Date Detail:
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Created Date: 1954-12-01 Completed Date: 2003-05-01 Revised Date: 2010-09-14 |
Medline Journal Info:
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Nlm Unique ID: 2985109R Medline TA: J Exp Med Country: Not Available |
Other Details:
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Languages: eng Pagination: 667-78 Citation Subset: OM |
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| MeSH Terms | |
Descriptor/Qualifier:
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Leukocytes* Myocarditis / complications* Rickettsia* |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
| Full Text | |
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Journal Information Journal ID (nlm-ta): J Exp Med ISSN: 0022-1007 ISSN: 1540-9538 Publisher: The Rockefeller University Press |
Article Information Download PDF  Copyright © Copyright, 1953, by The Rockefeller Institute for Medical Research New York Received Day: 6 Month: 8 Year: 1953 Print publication date: Day: 30 Month: 11 Year: 1953 Volume: 98 Issue: 6 First Page: 667 Last Page: 678 ID: 2136335 PubMed Id: 13109116 |
| MYOCARDITIS AND PULMONARY ARTERITIS IN MICE ASSOCIATED WITH THE PRESENCE OF RICKETTSIA-LIKE BODIES IN POLYMORPHONUCLEAR LEUCOCYTES | |
| Alwin M. Pappenheimer | |
| Joan B. Daniels | |
| From the Department of Bacteriology and Immunology, Harvard Medical School, and the Massachusetts Department of Public Health, Boston |
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