Document Detail


Myocarditis in systemic lupus erythematosus.
MedLine Citation:
PMID:  12401537     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although clinical manifestations of myocarditis in systemic lupus erythematosus are uncommon, noninvasive cardiac testing may detect subclinical cases. The pathogenesis of myocarditis in systemic lupus erythematosus has been ascribed to many factors, including autoimmunity, medications, and coexisting diseases. Lupus myocarditis merits urgent clinical attention because of the likely progression to arrhythmias, conduction disturbances and heart block, dilated cardiomyopathy, and heart failure. Endomyocardial biopsy can be used to identify the underlying inflammatory histopathology. Usual therapy includes high-dose corticosteroids, in addition to standard cardiac medications.
Authors:
Mevan Wijetunga; Stanley Rockson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of medicine     Volume:  113     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  2002 Oct 
Date Detail:
Created Date:  2002-10-28     Completed Date:  2002-11-13     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  419-23     Citation Subset:  AIM; IM    
Affiliation:
Department of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
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MeSH Terms
Descriptor/Qualifier:
Humans
Lupus Erythematosus, Systemic / complications*,  pathology*,  therapy
Myocarditis / etiology*,  pathology*,  therapy

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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