Document Detail

Myocarditis in infants and children: A review for the paediatrician.
MedLine Citation:
PMID:  20084124     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Clinical myocarditis is uncommon in infants and children. The most common pathogen is Coxsackievirus B. The offending agent triggers an immune response, which results in myocardial edema with subsequent impairment of systolic and diastolic function. Newborns and infants are more severely affected because the immature myocardium has limited ways of adapting to an acute insult. Children typically present with sinus tachycardia and gallop on auscultation, cardiomegaly on chest x-ray and small voltages on electrocardiogram. The echocardiogram shows reduced ventricular function. Viral studies can isolate the pathogen. Myocardial biopsy is useful diagnostically, but carries a significant risk for the sick infant. The first line of treatment includes measures such as rest, oxygen and diuretics. Inotropic agents are useful in moderate to severe heart failure. The role of immunosuppressive therapy is not yet clearly established in the paediatric age group. Prognosis is guarded in newborns but more favourable in older children.
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Paediatrics & child health     Volume:  6     ISSN:  1918-1485     ISO Abbreviation:  Paediatr Child Health     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2010-01-19     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  9815960     Medline TA:  Paediatr Child Health     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  543-5     Citation Subset:  -    
Division of Pediatric Cardiology, Montreal Children's Hospital, McGill University, Montreal, Quebec.
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