| Myocarditis as a complication in scleroderma patients with myositis. | |
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MedLine Citation:
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PMID: 8168276 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This report describes six diffuse scleroderma (PSS) patients with skeletal muscle myositis accompanied by severe myocarditis, diagnosed by CPK-MB elevation in conjunction with severe left ventricular (LV) hypokinesis. Although the myositis improved with steroid therapy in all patients, those treated with steroids alone died due to progressive LV failure. This experience suggests that the LV dysfunction in PSS patients with myositis may have an inflammatory component. Since the myocarditis may not be clinically apparent initially, it is suggested that CPK-MB fractionation and studies of LV function are undertaken in all PSS patients with myositis. The optimal treatment of this disorder, however, has yet to be determined. |
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Authors:
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L D Kerr; H Spiera |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Clinical cardiology Volume: 16 ISSN: 0160-9289 ISO Abbreviation: Clin Cardiol Publication Date: 1993 Dec |
Date Detail:
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Created Date: 1994-06-01 Completed Date: 1994-06-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7903272 Medline TA: Clin Cardiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 895-9 Citation Subset: IM |
Affiliation:
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Mount Sinai School of Medicine, Division of Rheumatology, New York, New York 10029. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Biopsy Clinical Enzyme Tests Creatine Kinase / blood Female Humans Isoenzymes Middle Aged Myocarditis / diagnosis, etiology*, pathology Myocardium / pathology Myositis / complications* Scleroderma, Systemic / complications* |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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