Document Detail

Myocardial stunning in man.
MedLine Citation:
PMID:  12766494     Owner:  NLM     Status:  MEDLINE    
Myocardial stunning refers to the contractile dysfunction that occurs following an episode of acute ischaemia, despite the return of normal blood flow. The phenomenon was initially identified in animal models, where it has been very well characterised, and there was initial doubt about whether a similar syndrome occurred in humans, and if it did, whether it was of any clinical relevance. This article outlines the conditions that must be met to diagnose myocardial stunning and why it has been difficult to confirm its presence in humans. The clinical scenarios where it has now been clearly identified and those others where it may also occur and be of clinical importance are also reviewed.
Edward Barnes; Masood A Khan
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Heart failure reviews     Volume:  8     ISSN:  1382-4147     ISO Abbreviation:  Heart Fail Rev     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-05-26     Completed Date:  2003-09-04     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9612481     Medline TA:  Heart Fail Rev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  155-60     Citation Subset:  IM    
Department of Cardiology, Great Western Hospital, Swindon, UK.
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MeSH Terms
Coronary Circulation / physiology
Myocardial Contraction / physiology
Myocardial Stunning / etiology*,  pathology,  physiopathology
Ventricular Dysfunction, Left / etiology,  pathology,  physiopathology

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