| Myocardial structure and matrix metalloproteinases. | |
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MedLine Citation:
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PMID: 22519443 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Metalloproteinases (MMPs) are enzymes which enhance proteolysis of extracellular matrix proteins. The pathophysiologic and prognostic role of MMPs has been demonstrated in numerous studies. The present review covers a wide a range of topics with regards to MMPs structural and functional properties, as well as their role in myocardial remodeling in several cardiovascular diseases. Moreover, the clinical and therapeutic implications from their assessment are highlighted. |
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Authors:
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C Aggeli; P Pietri; I Felekos; L Rautopoulos; K Toutouzas; E Tsiamis; C Stefanadis |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-4-20 |
Journal Detail:
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Title: Current topics in medicinal chemistry Volume: - ISSN: 1873-4294 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-4-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101119673 Medline TA: Curr Top Med Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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14 Argirokastrou St, Vrilisia, P.O 15235, Athens, Greece. caggeli@otenet.gr. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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