Document Detail


Myocardial structure and matrix metalloproteinases.
MedLine Citation:
PMID:  22519443     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Metalloproteinases (MMPs) are enzymes which enhance proteolysis of extracellular matrix proteins. The pathophysiologic and prognostic role of MMPs has been demonstrated in numerous studies. The present review covers a wide a range of topics with regards to MMPs structural and functional properties, as well as their role in myocardial remodeling in several cardiovascular diseases. Moreover, the clinical and therapeutic implications from their assessment are highlighted.
Authors:
C Aggeli; P Pietri; I Felekos; L Rautopoulos; K Toutouzas; E Tsiamis; C Stefanadis
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-20
Journal Detail:
Title:  Current topics in medicinal chemistry     Volume:  -     ISSN:  1873-4294     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101119673     Medline TA:  Curr Top Med Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
14 Argirokastrou St, Vrilisia, P.O 15235, Athens, Greece. caggeli@otenet.gr.
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