| Myocardial scintigraphy after pacemaker implantation for congenital complete atrioventricular block. | |
| | |
MedLine Citation:
|
PMID: 17345095 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Patients with isolated congenital complete atrioventricular block (CCAVB) occasionally develop dilated cardiomyopathy (DCM), despite early pacemaker implantation. However, the etiology of the DCM and its relationship to permanent ventricular pacing are not fully understood. Twenty-five patients with CCAVB underwent (99m) technetium (Tc) myocardial perfusion scintigraphy. Five patients were studied before and after pacing, providing a total of 30 image sets, which were divided into three groups; group 1: CCAVB before pacemaker implantation (PMI) (n = 11); group 2: CCAVB after PMI who did not subsequently develop DCM (n = 13); group 3: CCAVB after PMI who subsequently developed DCM (n = 6). Perfusion defects on single-photon-emission computed tomography (SPECT) were identified in group 1, 0 of 11 patients; group 2, 85% of patients; and group 3, 100% of patients. In groups 2 and 3, in patients with right ventricular pacing, the perfusion defects were mainly in the septum or between the apex and septum. On 20 segments' polar maps, the distribution of %uptake showed a similar pattern in groups 2 and 3, the degree of decreased %uptake and the number of segments with decreased %uptake being more severe in group 3. "Artificial" left bundle branch block (LBBB) pattern myocardial contraction induced by right ventricular pacing decreased myocardial perfusion around the apex and septum. Some patients with CCAVB will develop left ventricular dysfunction caused by artificial LBBB-induced interventricular asynchrony. |
| | |
Authors:
|
Hisashi Takasugi; Ken Watanabe; Yasuo Ono; Heima Sakaguchi; Noriko Motoki; Yoko Yoshida; Shigeyuki Echigo; Kazuki Fukuchi; Yoshio Ishida |
Related Documents
:
|
15817085 - Limited benefit of septal pre-excitation in pace prevention of atrial fibrillation. 7094445 - The acute electrophysiological effects of intravenous metoprolol. 16008815 - Postmortem anatomy of the coronary sinus pacing lead. 17897135 - Use of a retained guidewire to improve the left ventricular pacing threshold. 3904535 - The clinical spectrum of tricuspid regurgitation detected by pulsed doppler echocardiog... 3385205 - Mechanisms of partial renal infarct hypertension. |
Publication Detail:
|
Type: Journal Article Date: 2007-03-08 |
Journal Detail:
|
Title: European journal of pediatrics Volume: 167 ISSN: 1432-1076 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 2008 Feb |
Date Detail:
|
Created Date: 2007-12-24 Completed Date: 2008-05-22 Revised Date: 2008-06-05 |
Medline Journal Info:
|
Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: Germany |
Other Details:
|
Languages: eng Pagination: 183-8 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, National Cardiovascular Center, Suita, Osaka, Japan. takasugi@kochi-u.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Adult Atrioventricular Block / physiopathology, radionuclide imaging, therapy* Child Child, Preschool Coronary Circulation Female Gated Blood-Pool Imaging Heart / radionuclide imaging* Humans Infant Male Myocardial Contraction Myocardium / metabolism* Organophosphorus Compounds / pharmacokinetics Organotechnetium Compounds / pharmacokinetics Pacemaker, Artificial* Stroke Volume Tomography, Emission-Computed, Single-Photon |
| Chemical | |
Reg. No./Substance:
|
0/Organophosphorus Compounds; 0/Organotechnetium Compounds; 0/technetium Tc 99m 1,2-bis(bis(2-ethoxyethyl)phosphino)ethane |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Endothelial dysfunction in adult patients with a history of Kawasaki disease.
Next Document: Scimitar syndrome: incidence, treatment, and prognosis.