Document Detail

Myocardial scarring following chemotherapy for multiple myeloma detected using late gadolinium hyperenhancement cardiovascular magnetic resonance.
MedLine Citation:
PMID:  19584744     Owner:  NLM     Status:  MEDLINE    
We present the case of a 60-year-old lady who was treated with chemotherapy for myeloma. Following initiation of bortezomib, she developed heart failure which was associated with a reduction in left ventricular systolic function. A gadolinium enhanced cardiovascular magnetic resonance scan demonstrated midwall hyperenhancement consistent with midwall fibrosis.
Paul W X Foley; Malcolm S Hamilton; Francisco Leyva
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiovascular medicine (Hagerstown, Md.)     Volume:  11     ISSN:  1558-2035     ISO Abbreviation:  J Cardiovasc Med (Hagerstown)     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-03-30     Completed Date:  2010-06-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101259752     Medline TA:  J Cardiovasc Med (Hagerstown)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  386-8     Citation Subset:  IM    
Department of Cardiology, Good Hope Hospital, Sutton Coldfield, UK.
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MeSH Terms
Antineoplastic Agents / adverse effects*
Boronic Acids / adverse effects*
Fatal Outcome
Gadolinium / diagnostic use*
Heart Failure / chemically induced*,  pathology
Magnetic Resonance Imaging
Middle Aged
Multiple Myeloma / drug therapy
Myocardium / pathology
Pyrazines / adverse effects*
Reg. No./Substance:
0/Antineoplastic Agents; 0/Boronic Acids; 0/Pyrazines; 0/bortezomib; 7440-54-2/Gadolinium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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