Document Detail

Myocardial protection during aortic valve replacement: normothermia versus hypothermia.
MedLine Citation:
PMID:  630459     Owner:  NLM     Status:  MEDLINE    
The operative results in 32 patients who underwent aortic valve replacement with aortic occlusion and normothermic myocardium (group 1) were compared with 54 similar patients in whom the myocardium was protected by hypothermic coronary perfusion through the aortic root (group 2). The operative mortality and the incidence of heart failure, subendocardial ischemia and myocardial infarction were the same in the two groups. The maximal concentrations of cardiac enzymes after operation in group 2 patients were significantly lower than those in group 1. The postoperative cardiac performance was significantly different in that only 5.6% of group 2 patients required inotropic agents after operation compared with 25% of group 1 patients. The patients in group 2 were easier to defibrillate after cardiopulmonary bypass.
M Haraphongse; R S Fraser; R E Rossall; R L Fisk; C A Basuldo; E T Gelfand; J C Callaghan
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Canadian journal of surgery. Journal canadien de chirurgie     Volume:  21     ISSN:  0008-428X     ISO Abbreviation:  Can J Surg     Publication Date:  1978 Mar 
Date Detail:
Created Date:  1978-05-17     Completed Date:  1978-05-17     Revised Date:  2007-08-16    
Medline Journal Info:
Nlm Unique ID:  0372715     Medline TA:  Can J Surg     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  101-3     Citation Subset:  IM    
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MeSH Terms
Aortic Valve / surgery*
Heart Diseases / complications
Heart Valve Prosthesis / methods*,  mortality
Hypothermia, Induced*
Middle Aged
Myocardial Contraction / drug effects
Perfusion / methods
Postoperative Complications
Stimulation, Chemical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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