| Myocardial and peripheral concentrations of beta-endorphin before and following myocardial ischemia and reperfusion during coronary angioplasty. | |
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MedLine Citation:
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PMID: 15240957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is substantial evidence indicating that endogenous opioid peptides are involved in the pathophysiology of myocardial ischemia and reperfusion. We measured the myocardial and peripheral concentrations of beta-endorphin before and following myocardial ischemia and reperfusion during coronary angioplasty. The results indicate that in patients with coronary artery disease, there was an augmented myocardial concentration of beta-endorphin. Moreover, there was an increased peripheral concentration of beta-endorphin following myocardial ischemia and reperfusion. The data support the previous notion that endogenous opioid peptides are involved in the pathophysiology of ischemic heart disease. |
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Authors:
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Michael Chich-Kuang Chang; Andrew Ying-Siu Lee; Wen-Ye Lin; Tien-Jen Chen; Miin-Yaw Shyu; Wen-Fung Chang |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Japanese heart journal Volume: 45 ISSN: 0021-4868 ISO Abbreviation: Jpn Heart J Publication Date: 2004 May |
Date Detail:
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Created Date: 2004-07-08 Completed Date: 2004-08-10 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401175 Medline TA: Jpn Heart J Country: Japan |
Other Details:
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Languages: eng Pagination: 365-71 Citation Subset: IM |
Affiliation:
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Division of Cardiology, Jen Ai Hospital, Tali, Taichung. Taiwan, ROC. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Angioplasty, Transluminal, Percutaneous Coronary* Blood Pressure Coronary Disease / blood*, physiopathology, therapy Creatine Kinase / blood Creatine Kinase, MB Form Female Heart Rate Humans Isoenzymes / blood Lactic Acid / blood Male Middle Aged Myocardial Ischemia / blood*, physiopathology Myocardial Reperfusion* Myocardium / chemistry* Pulmonary Wedge Pressure Stroke Volume beta-Endorphin / analysis, blood* |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; 50-21-5/Lactic Acid; 60617-12-1/beta-Endorphin; EC 2.7.3.2/Creatine Kinase; EC 2.7.3.2/Creatine Kinase, MB Form |
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