| Myocardial perfusion imaging after transient balloon occlusion during percutaneous coronary interventions. | |
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MedLine Citation:
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PMID: 17386385 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Myocardial perfusion imaging (MPI) is highly sensitive in detecting rest ischemia when the radiotracer is injected during the episode of ischemia. The frequency of abnormal MPI results after resolution of ischemia is not well defined. The aim of this study was to determine how long MPI results remain abnormal after transient coronary artery occlusion. METHODS AND RESULTS: Patients undergoing single-vessel percutaneous coronary intervention were injected with technetium 99m sestamibi at 30 to 60 minutes (group 1) (n = 20) or 90 to 120 minutes (group 2) (n = 10) after the last balloon inflation and 24 hours later. There were 30 men aged 59 +/- 8 years. The culprit vessel was the left anterior descending artery in 14 patients and the right coronary artery in 13. The diameter stenosis was reduced from 76.1% +/- 8.7% to 3.0% +/- 6.4% (P < .001). The duration of balloon inflation was 40.3 +/- 12.5 seconds. Chest pain or ST shifts occurred in 66% of patients. A perfusion defect in the territory of the culprit artery was detected in 3 of 20 patients (15%) in group 1 and in 0 of 10 patients (0%) in group 2 (P = .3). One of those three patients had a perfusion defect on MPI done 24 hours later, along with a regional wall motion abnormality on the 2 sets of images. CONCLUSIONS: Abnormal perfusion is seen in a small percentage of patients at 30 to 60 minutes and in none at 90 to 120 minutes after a brief transient balloon occlusion. These results might have important implications in patient care. |
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Authors:
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Raed Aqel; Gilbert J Zoghbi; Luvenia W Bender; Johnny W Scott; Jon A Baldwin; Jaekyeong Heo; Ami E Iskandrian |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology Volume: 14 ISSN: 1532-6551 ISO Abbreviation: J Nucl Cardiol Publication Date: 2007 Apr |
Date Detail:
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Created Date: 2007-03-27 Completed Date: 2007-04-19 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9423534 Medline TA: J Nucl Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 221-8 Citation Subset: IM |
Affiliation:
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Birmingham VA Medical Center, University of Alabama at Birmingham, Birmingham, Ala 35294, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Angioplasty, Transluminal, Percutaneous Coronary* Balloon Occlusion* Coronary Artery Disease / complications, radionuclide imaging*, therapy* Humans Male Middle Aged Radiopharmaceuticals / diagnostic use Reproducibility of Results Sensitivity and Specificity Single-Blind Method Technetium Tc 99m Sestamibi / diagnostic use* Treatment Outcome Ventricular Dysfunction, Left / etiology, radionuclide imaging*, therapy* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 109581-73-9/Technetium Tc 99m Sestamibi |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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