Document Detail

Myocardial perfusion at fatal infarction: location and size of scintigraphic defects.
MedLine Citation:
PMID:  1531072     Owner:  NLM     Status:  MEDLINE    
In a consecutive study of myocardial scintigraphy in acute ischemic syndrome, four patients had 99mTc-hexamibi injected intravenously before they developed fatal cardiogenic shock. Planar scintigraphy was performed after death. Slices of the hearts after autopsy were analyzed for scintigraphic and pathoanatomic abnormalities. Location of perfusion defects in planar views of the heart was in good agreement with the scintigraphied, sliced sections. The extent of infarction judged from inspection and formasan staining was much smaller (7%-40% and 6%-43% of the total slice area) than found at scintigraphy, where 83%-92% of the myocardium showed ischemia as defined by a 99mTc-hexamibi uptake below an arbitrary limit on half maximum uptake. Myocardial hypoperfusion might thus aggravate the functional impairment at myocardial infarction and lead to cardiogenic shock.
K Hvid-Jacobsen; J T Møller; E Kjøller; S L Nielsen; U Engel; S Duus; I L Kanstrup; P F Jensen; J Carlsen; F Nielsen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of nuclear medicine : official publication, Society of Nuclear Medicine     Volume:  33     ISSN:  0161-5505     ISO Abbreviation:  J. Nucl. Med.     Publication Date:  1992 Feb 
Date Detail:
Created Date:  1992-02-21     Completed Date:  1992-02-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0217410     Medline TA:  J Nucl Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
Department of Clinical Physiology/Nuclear Medicine, Herlev Hospital, University of Copenhagen, Denmark.
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MeSH Terms
Coronary Circulation*
Coronary Disease / pathology,  radionuclide imaging*
Heart / radionuclide imaging*
Myocardium / pathology
Organotechnetium Compounds / diagnostic use*
Prospective Studies
Technetium Tc 99m Sestamibi
Reg. No./Substance:
0/Organotechnetium Compounds; 109581-73-9/Technetium Tc 99m Sestamibi

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