| Myocardial and non-myocardial release of myoglobin and creatine-kinase MB following cardiac operations with hypothermic potassium cardioplegia. | |
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MedLine Citation:
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PMID: 6979388 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Serum time-activity curves for myoglobin, creatine-kinase (CK) and its isoenzyme MB were determined during and after coronary bypass surgery and aortic valve replacement. Hypothermic potassium cardioplegia was the method employed to initiate cardiac arrest. Cardiac myoglobin and CK-MB release rates were maximal 0.5 to 1.0 h post aortic cross-clamp release (PACR) with maximal concentrations at 1 and 4 h PACR respectively. The cardiac release ceased within 5 h PACR but was followed by a noncardiac release with maximal concentrations from 10 to 35 h PACR. The cardiac myoglobin release was significantly lower in the coronary bypass group, whereas no significant intergroup difference was observed for CK-MB. The cumulative CK-MB release corresponded roughly to about 5 g of myocardium. |
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Authors:
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J C Sylvén; V Bomfim; T Ivert; C Olin |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Cardiovascular research Volume: 16 ISSN: 0008-6363 ISO Abbreviation: Cardiovasc. Res. Publication Date: 1982 Mar |
Date Detail:
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Created Date: 1982-08-07 Completed Date: 1982-08-07 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0077427 Medline TA: Cardiovasc Res Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 151-7 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aortic Valve
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surgery Cold Temperature / adverse effects* Coronary Artery Bypass Creatine Kinase / blood* Heart Arrest, Induced / adverse effects*, methods Heart Valve Prosthesis Humans Isoenzymes Male Middle Aged Myocardium / metabolism Myoglobin / blood* |
| Chemical | |
Reg. No./Substance:
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0/Isoenzymes; 0/Myoglobin; EC 2.7.3.2/Creatine Kinase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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