Document Detail


Myocardial morphology in rabbits exposed to various gas-phase constituents of tobacco smoke--an ultrastructural study.
MedLine Citation:
PMID:  6272820     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Rabbits were continuously exposed to 200 ppm carbon monoxide. Using the same criteria as applied by earlier investigators for morphological myocardial damage, no histotoxic effect on myocardial morphology could be demonstrated when electron-microscopic investigations were performed blindly. Similarly, exposure to 0.5 ppm hydrogen cyanide, 0.5 ppm hydrogen cyanide + 200 ppm carbon monoxide, 0.5 ppm hydrogen cyanide + 200 ppm carbon monoxide + 5 ppm nitric oxide and to 50 ppm carbonyl sulphide for 1-7 weeks had no significant effect on myocardial ultrastructure.
Authors:
C Hugod
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Atherosclerosis     Volume:  40     ISSN:  0021-9150     ISO Abbreviation:  Atherosclerosis     Publication Date:  1981 Oct 
Date Detail:
Created Date:  1982-01-20     Completed Date:  1982-01-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0242543     Medline TA:  Atherosclerosis     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  181-90     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Carbon Monoxide / pharmacology
Heart / drug effects
Hydrogen Cyanide / pharmacology
Male
Myocardium / ultrastructure*
Nitric Oxide / pharmacology
Plants, Toxic*
Rabbits
Smoke*
Sulfur Oxides / pharmacology
Tobacco*
Chemical
Reg. No./Substance:
0/Smoke; 0/Sulfur Oxides; 10102-43-9/Nitric Oxide; 463-58-1/carbonyl sulfide; 630-08-0/Carbon Monoxide; 74-90-8/Hydrogen Cyanide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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