| Myocardial microangiopathy associated with antiphospholipid antibodies. | |
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MedLine Citation:
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PMID: 11237124 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Myocardial thrombotic microangiopathy is a well described post-mortem finding in patients with the catastrophic antiphospholipid (APL) syndrome. However, it has been only very rarely imaged in living patients. Here, we report two patients with APL antibodies presenting with scintigraphic, electrocardiographic and/or echocardiographic evidence of (sub)acute myocardial ischaemia, despite a normal coronary angiography. Formal proof of a thrombotic microangiopathy was obtained by a kidney biopsy in one patient. We emphasize the value of 99mTc-MIBI (2-methoxy isobutyl isonitrile) exercise stress myocardial scintigraphy for the detection of cardiac microangiopathy associated with the APL syndrome. |
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Authors:
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B R Lauwerys; M Lambert; J L Vanoverschelde; J P Cosyns; F A Houssiau |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Lupus Volume: 10 ISSN: 0961-2033 ISO Abbreviation: Lupus Publication Date: 2001 |
Date Detail:
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Created Date: 2001-03-09 Completed Date: 2001-06-14 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9204265 Medline TA: Lupus Country: England |
Other Details:
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Languages: eng Pagination: 123-5 Citation Subset: IM |
Affiliation:
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Rheumatology Department, Cliniques Universitaires Saint-Luc, Université catholique de Louvain, Bruxelles, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antibodies, Antiphospholipid* Antiphospholipid Syndrome* Coronary Disease* Female Humans |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Antiphospholipid |
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