| Myocardial ischemia and stunning induced by topical intranasal phenylephrine pledgets. | |
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MedLine Citation:
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PMID: 9433094 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This case study describes myocardial ischemia and stunning after the topical application of phenylephrine-soaked pledgets (0.25%) in a 63-year-old female undergoing elective endoscopic sinus surgery. The patient had no previous history of cardiovascular disease or illicit drug use. Transient myocardial ischemia was associated with acute hypertension, chest pain, and S-T segment changes 4 minutes after pledget placement. Angiography revealed normal coronary blood flow and severe left ventricular systolic and diastolic dysfunction. Follow-up echocardiography demonstrated improved left ventricular function within 1 week and total resolution of dysfunction by 4 weeks after ischemia. |
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Authors:
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R B Hecker; J V Hays; J D Champ; B J Rubal |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Military medicine Volume: 162 ISSN: 0026-4075 ISO Abbreviation: Mil Med Publication Date: 1997 Dec |
Date Detail:
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Created Date: 1998-02-09 Completed Date: 1998-02-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 2984771R Medline TA: Mil Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 832-5 Citation Subset: IM |
Affiliation:
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Anesthesia and Operative Service, Brooke Army Medical Center, Fort Sam Houston, TX 78234-6200, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Administration, Intranasal Adrenergic alpha-Agonists / administration & dosage, adverse effects* Female Humans Middle Aged Myocardial Ischemia / chemically induced* Myocardial Stunning / chemically induced* Phenylephrine / administration & dosage, adverse effects* Recurrence Sinusitis / surgery |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Agonists; 59-42-7/Phenylephrine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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