Document Detail

Myocardial ischemia in sedated patients undergoing fiberoptic bronchoscopy.
MedLine Citation:
PMID:  9404738     Owner:  NLM     Status:  MEDLINE    
STUDY OBJECTIVE: To study the incidence of myocardial ischemia and related hemodynamic alterations in sedated patients undergoing fiberoptic bronchoscopy (FOB). DESIGN: Prospective study. SETTING: Tertiary care, university hospital. PATIENTS: Twenty-nine patients, age 50 years or older, undergoing elective FOB. INTERVENTIONS: Myocardial ischemia was assessed by continuous ECG monitoring beginning 30 min before, and until 2 h after FOB. MEASUREMENTS AND RESULTS: During FOB, there was a significant rise in heart rate (89+/-3 [mean+/-SE] to 120+/-4 beats/min) and fall in oxygen saturation (95+/-1 to 90+/-1%). There was no significant rise in systolic or diastolic BP. Five patients (17%) had myocardial ischemia during FOB that lasted 20+/-8 min. Their demographic and pre-FOB characteristics were not different from the other patients. Compared to baseline values, a significant rise in heart rate, a fall in oxygen saturation, and no significant change in BP were observed during FOB in patients, both with or without ischemia. Although not statistically significant, ischemia was associated with more protracted procedures. CONCLUSIONS: Myocardial ischemia may develop in elderly patients undergoing FOB. This observation encourages the routine use of ECG and oximetry during FOB, allowing for early intervention to prevent the dangerous combination of hypoxia, tachycardia, and myocardial ischemia. Moreover, this study suggests that methods to ensure oxygenation during FOB should be adhered to, and that the routine administration of atropine should be reconsidered.
I Matot; M R Kramer; L Glantz; B Drenger; S Cotev
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chest     Volume:  112     ISSN:  0012-3692     ISO Abbreviation:  Chest     Publication Date:  1997 Dec 
Date Detail:
Created Date:  1998-01-06     Completed Date:  1998-01-06     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0231335     Medline TA:  Chest     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1454-8     Citation Subset:  AIM; IM    
Department of Anesthesiology and Critical Care Medicine, Hadassah University School of Medicine, Jerusalem, Israel.
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MeSH Terms
Anesthesia, Inhalation
Bronchoscopy / adverse effects*,  methods
Chi-Square Distribution
Conscious Sedation*
Fiber Optic Technology / instrumentation
Middle Aged
Myocardial Ischemia / epidemiology,  etiology*,  physiopathology
Prospective Studies
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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