Document Detail


Myocardial ischemia in patients with dilated cardiomyopathy.
MedLine Citation:
PMID:  20808261     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dilated cardiomyopathy (DCM) is characterized by ventricular chamber enlargement and systolic dysfunction with normal ventricular wall thickness. More recent studies have shown that the coronary microcirculation may be directly affected in cardiomyopathies. Left ventricular regional myocardial perfusion, wall motion, and metabolism abnormalities are often present in patients with DCM. These data support the possibility that myocardial ischemia may play an important role in the development of DCM and have important prognostic value in patients with DCM. We need to pay attention to the assessment of myocardial blood flow and myocardial ischemia in patients with DCM. Furthermore, anti-ischemic therapy may improve left ventricular function and clinical outcomes in patients with heart failure resulted from DCM.
Authors:
Wei Fang; Jian Zhang; Zuo-Xiang He
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Nuclear medicine communications     Volume:  31     ISSN:  1473-5628     ISO Abbreviation:  Nucl Med Commun     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-30     Completed Date:  2011-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8201017     Medline TA:  Nucl Med Commun     Country:  England    
Other Details:
Languages:  eng     Pagination:  981-4     Citation Subset:  IM    
Affiliation:
Department of Nuclear Medicine, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
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MeSH Terms
Descriptor/Qualifier:
Cardiomyopathy, Dilated / complications*,  diagnosis,  metabolism,  physiopathology
Coronary Circulation / drug effects
Humans
Myocardial Ischemia / complications*,  drug therapy,  metabolism,  physiopathology
Myocardium / metabolism
Prognosis

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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