Document Detail

Myocardial involvement in systemic lupus erythematosus and systemic sclerosis--pulsed Doppler echocardiographic evaluation of left ventricular diastolic function.
MedLine Citation:
PMID:  1299414     Owner:  NLM     Status:  MEDLINE    
Myocardial involvement (MI) in connective tissue diseases is commonly found at autopsy but seldom recognized clinically. To assess the subclinical MI, the left ventricular (LV) diastolic function was studied in 16 patients with systemic lupus erythematosus (SLE) and 15 patients with systemic sclerosis (SSc) by means of pulsed Doppler echocardiography. Patients with abnormal LV systolic function were not included. A control group (C) included 16 sex and age-matched healthy subjects. The parameters analyzed were: peak early diastolic flow velocity (E), peak late diastolic flow velocity (A), E/A ratio, isovolumic relaxation time (IRT). LV diastolic function was found impaired in SLE and SSc patients even when systolic function was normal as could be demonstrated by pulsed Doppler echocardiography.
C Stănescu; G A Dan
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Romanian journal of internal medicine = Revue roumaine de médecine interne     Volume:  30     ISSN:  1220-4749     ISO Abbreviation:  Rom J Intern Med     Publication Date:    1992 Oct-Dec
Date Detail:
Created Date:  1993-05-18     Completed Date:  1993-05-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9304507     Medline TA:  Rom J Intern Med     Country:  ROMANIA    
Other Details:
Languages:  eng     Pagination:  243-8     Citation Subset:  IM    
N. Gh. Lupu Institute of Internal Medicine, Bucharest, Romania.
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MeSH Terms
Cardiomyopathies / etiology,  physiopathology,  ultrasonography*
Echocardiography, Doppler*
Lupus Erythematosus, Systemic / complications,  physiopathology,  ultrasonography*
Scleroderma, Systemic / complications,  physiopathology,  ultrasonography*
Ventricular Function, Left*

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