| Myocardial infarction in the 1990s. The importance of early thrombolytic therapy. | |
| | |
MedLine Citation:
|
PMID: 7753739 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Substantial advances in the diagnosis and treatment of ischemic heart disease, especially myocardial infarction, have reduced mortality rates during the past several years. This progress is tempered, however, by the continuing large overall incidence of myocardial infarction and cardiac death in persons in their prime years. Preventive measures are important and are usually best applied by primary care physicians. The acute crisis of coronary artery thrombosis demands accurate diagnosis and timely thrombolytic therapy, which has halved the mortality rate of myocardial infarction. Several effective thrombolytic agents are available; on the basis of several large international trials of these drugs, it appears that the benefits of early and appropriate use of any one of these agents outweigh any individual advantages. In addition to thrombolytics, aspirin and heparin are necessary adjunctive drugs for acute myocardial infarction. Nitroglycerin is helpful, but its essential role seems less evident. Earlier use of beta blockers and angiotensin-converting enzyme inhibitors has been proved effective in reducing mortality. Percutaneous transluminal coronary angioplasty is definitely as effective as thrombolytic therapy, but immediate application is logistically challenging in most US hospitals. |
| | |
Authors:
|
R E Fowles |
Related Documents
:
|
2660919 - Thrombolytic therapy and acute myocardial infarction. 7904119 - Early intravenous beta blockade and thrombolytics in acute myocardial infarction. 10506849 - The state of lipid peroxidation and antioxidants following thrombolytic therapy with rt... 10172669 - Alteplase: a pharmacoeconomic evaluation of its use in the management of myocardial inf... 1904189 - Long-term effect of thrombolytic therapy on left ventricular ejection fraction after ac... 2662739 - Comparison of thrombolytic agents: selected hematologic, vascular and clinical events. 7754949 - Early improvement in congestive heart failure after correction of secondary mitral regu... 12581679 - Prevalence of left ventricular diastolic dysfunction in the community. results from a d... 15949739 - Experience of percutaneous coronary intervention in the management of pediatric cardiac... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Review |
Journal Detail:
|
Title: Postgraduate medicine Volume: 97 ISSN: 0032-5481 ISO Abbreviation: Postgrad Med Publication Date: 1995 May |
Date Detail:
|
Created Date: 1995-06-16 Completed Date: 1995-06-16 Revised Date: 2008-11-21 |
Medline Journal Info:
|
Nlm Unique ID: 0401147 Medline TA: Postgrad Med Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 135-8, 141-2, 145-6 Citation Subset: AIM; IM |
Affiliation:
|
Salt Lake Clinic, UT 84102, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adrenergic beta-Antagonists
/
therapeutic use Aged Angioplasty, Transluminal, Percutaneous Coronary Aspirin / therapeutic use Clinical Trials as Topic Drug Therapy, Combination Heparin / therapeutic use Humans Middle Aged Myocardial Infarction / etiology, mortality, therapy* Nitroglycerin / therapeutic use Risk Factors Streptokinase / therapeutic use Time Factors Urokinase-Type Plasminogen Activator / therapeutic use Warfarin / therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Adrenergic beta-Antagonists; 50-78-2/Aspirin; 55-63-0/Nitroglycerin; 81-81-2/Warfarin; 9005-49-6/Heparin; EC 3.4.-/Streptokinase; EC 3.4.21.73/Urokinase-Type Plasminogen Activator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Henoch-Schönlein purpura. A multisystem disease also seen in adults.
Next Document: No ice, no butter. Advice on management of burns for primary care physicians.