Document Detail

Myocardial infarction following surgical operations.
MedLine Citation:
PMID:  5723723     Owner:  NLM     Status:  MEDLINE    
One hundred and forty-one randomly selected surgical patients, aged 35 years or over, were studied preoperatively, followed through their operative procedures, and reassessed during the first post-operative week for evidence of myocardial ischaemia associated with surgical operations under general anaesthesia. Of these patients 38% were found to have preoperative clinical evidence of heart disease, hypertension, or diabetes; 45% had abnormal preoperative E.C.G. patterns.Three patients experienced myocardial infarction during or within 36 hours of operation, all of the occult type; all were in the preoperative abnormal groups. Non-specific postoperative E.C.G. changes were equally common in the groups of patients with normal or abnormal preoperative electrocardiograms.A relationship existed between a rise in serum lactic dehydrogenase (L.D.H.) concentration and the field of the operation, but the diagnosis of infarction was not confused provided serum L.D.H. isoenzyme patterns and a rise in serum aspartate aminotransferase (S.G.O.T.) levels were consistent with the diagnosis.
P R Hunter; P Endrey-Walder; G E Bauer; F O Stephens
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  4     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1968 Dec 
Date Detail:
Created Date:  1969-01-28     Completed Date:  1969-01-28     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  725-8     Citation Subset:  AIM; IM    
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MeSH Terms
Aspartate Aminotransferases / blood
Diabetes Complications
Hypertension / complications
L-Lactate Dehydrogenase / blood
Middle Aged
Myocardial Infarction / diagnosis,  etiology*
Postoperative Complications*
Reg. No./Substance:
0/Isoenzymes; EC Dehydrogenase; EC Aminotransferases

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