| Myocardial infarction following recombinant tissue plasminogen activator treatment for acute ischemic stroke: a dangerous complication. | |
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MedLine Citation:
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PMID: 22931992 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Thrombolysis with intravenous tissue plasminogen activator (t-PA) is currently an approved therapy for patients with acute ischemic stroke. Acute myocardial infarction (AMI) immediately following t-PA treatment for stroke is a rare but serious complication. A case of acute myocardial infarction (MI) following IV t-PA infusion for acute stroke was observed. This is a 52-year-old male with a known history of hypertension and chest pain, who subsequently developed MI four hours after IV t-PA was administered for acute ischemic stroke. The disruption of intra-cardiac thrombus and subsequent embolization to the coronary arteries may be an important mechanism. In addition, spontaneous recanalization of infarct-related arteries may be associated with greater myocardial salvage and better prognosis. |
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Authors:
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Zhi-Gang Zhou; Rui-Lan Wang; Kang-Long Yu |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Chinese medical journal Volume: 125 ISSN: 0366-6999 ISO Abbreviation: Chin. Med. J. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-08-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7513795 Medline TA: Chin Med J (Engl) Country: China |
Other Details:
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Languages: eng Pagination: 2775-6 Citation Subset: IM |
Affiliation:
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Department of Emergency and Intensive Care Medicine, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai 201620, China. |
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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