Document Detail

Myocardial infarction following coronary artery bypass graft surgery increases healthcare resource utilization.
MedLine Citation:
PMID:  17414091     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To assess the health economic impact of perioperative myocardial infarction in a cohort of patients undergoing coronary artery bypass graft surgery. DESIGN: Retrospective cohort analysis using data from hospital bills and uniform billing forms. SETTING: A total of 147 geographically diverse hospitals in the United States. PATIENTS: The study population consisted of 2,102 coronary artery bypass graft surgery patients enrolled in the PRIMO-CABG trial at U.S. sites between January 2002 and February 2003. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Resource utilization and costs during the index hospitalization and during a 6-month follow-up period were compared between patients who had a myocardial infarction by postoperative day 4 and those who did not. Linear regression was used to examine whether myocardial infarction by day 4 was associated with index hospitalization costs, after adjusting for baseline characteristics. Myocardial infarction occurred in 191 (9.1%) patients undergoing coronary artery bypass graft surgery. Myocardial infarction was associated with a doubling of intensive care unit time (3.5 days among patients with no myocardial infarction and 7.1 days among patients with myocardial infarction, p < .01) and a 48% increase in hospital length of stay. Myocardial infarction by day 4 was associated with a 43% increase in hospital costs, a 29% increase in physician service costs, a 41% increase in total costs during the index hospitalization, and a 38% increase in cumulative 6-month costs. After baseline adjustment, myocardial infarction continued to be associated with higher index hospitalization costs. CONCLUSIONS: Myocardial infarction following coronary artery bypass graft surgery was associated with a significant increase in intensive care unit time, hospital length of stay, and overall costs, which contributed to greater hospital and physician service costs. Healthcare resource utilization is increased in patients sustaining a myocardial infarction following coronary artery bypass graft surgery.
John C Chen; Padma Kaul; Jerrold H Levy; Axel Haverich; Philippe Menasché; Peter K Smith; Michel Carrier; Edward D Verrier; Frans Van de Werf; Russel Burge; Paul Finnegan; Daniel B Mark; Stanton K Shernan;
Publication Detail:
Type:  Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Critical care medicine     Volume:  35     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-20     Completed Date:  2007-05-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1296-301     Citation Subset:  AIM; IM    
Division of Cardiothoracic Surgery, University of Hawaii School of Medicine, Honolulu, USA.
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MeSH Terms
Cohort Studies
Coronary Artery Bypass / adverse effects,  economics*
Follow-Up Studies
Health Resources / utilization*
Hospital Costs / statistics & numerical data*
Intensive Care Units / economics,  utilization
Length of Stay / economics
Linear Models
Multivariate Analysis
Myocardial Infarction / economics*,  etiology
Retrospective Studies
United States

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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