Document Detail

Myocardial infarction, circadian rhythm and delay in hospital admission.
MedLine Citation:
PMID:  2626108     Owner:  NLM     Status:  MEDLINE    
Circadian variations have been observed in the onset of acute coronary syndromes including acute myocardial infarction. We studied 422 acute myocardial infarction patients who presented to the coronary care unit of General Hospital Kuala Lumpur. Of the 318 (75.4%) patients whose data was complete, a circadian rhythm with bimodal peak was demonstrated. The second quarter of the day i.e. 6.00 a.m. to 12 noon was shown to have a significantly increased frequency of onset of acute myocardial infarction (p less than 0.05). Time delay in presenting to the hospital was also determined. This showed that 56.8% of acute myocardial infarction patients presented early, within four hours of the onset of symptoms. By six hours, more than 71% had sought hospital care. This early presentation to the hospital may offer a realistic opportunity for optimal thrombolytic therapy should this treatment modality be offered as routine to infarct patients.
D K Quek; S B Ong; L Y Lim
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Medical journal of Malaysia     Volume:  44     ISSN:  0300-5283     ISO Abbreviation:  Med. J. Malaysia     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1990-04-11     Completed Date:  1990-04-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361547     Medline TA:  Med J Malaysia     Country:  MALAYSIA    
Other Details:
Languages:  eng     Pagination:  14-22     Citation Subset:  IM    
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MeSH Terms
Aged, 80 and over
Circadian Rhythm*
Middle Aged
Myocardial Infarction / physiopathology*
Patient Admission*

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