Document Detail

Myocardial infarction associated with phenylpropanolamine.
MedLine Citation:
PMID:  10645839     Owner:  NLM     Status:  MEDLINE    
Phenylpropanolamine is a sympathomimetic agent widely used in over-the-counter and prescription decongestant medications. We describe a young woman without cardiac risk factors who sustained myocardial infarction after unintentional overuse of a nasal decongestant containing phenylpropanolamine. The pathophysiology of myocardial injury and current management strategies as related to this agent are discussed. Although serious adverse reactions to phenylpropanolamine are uncommon, potentially serious harm may be caused by this widely available drug in healthy individuals.
R Oosterbaan; M J Burns
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of emergency medicine     Volume:  18     ISSN:  0736-4679     ISO Abbreviation:  J Emerg Med     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-02-07     Completed Date:  2000-02-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8412174     Medline TA:  J Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM    
Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.
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MeSH Terms
Myocardial Infarction / chemically induced*,  physiopathology
Nasal Decongestants / poisoning*
Phenylpropanolamine / poisoning*
Sympathomimetics / poisoning*
Reg. No./Substance:
0/Nasal Decongestants; 0/Sympathomimetics; 14838-15-4/Phenylpropanolamine

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