| Myocardial infarct: depiction with contrast-enhanced MR imaging--comparison of gadopentetate and gadobenate. | |
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MedLine Citation:
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PMID: 16055693 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Institutional review board approval and patient written informed consent were obtained. On two separate occasions, 24 hours apart, contrast-enhanced cardiac magnetic resonance (MR) imaging was performed prospectively at 1, 3, 5, 10, and 20 minutes after injection of gadopentetate dimeglumine and gadobenate dimeglumine in 15 patients (11 men, four women) with history of myocardial infarction. Both agents allowed detection of infarcted myocardium. T1 values at all times were significantly (P < .05) lower for gadobenate, compared with values for gadopentetate, in both infarcted and noninfarcted myocardium. At 1 minute after administration of both agents, T1 values in left ventricular cavity (LVC) were not different; at 3-20 minutes after injection, values were significantly (P < .05) lower for gadobenate. Differences between contrast-to-noise ratio (CNR) values of infarcted and noninfarcted myocardium were significantly higher on gadobenate-enhanced images (P < .05). CNR values between infarcted myocardium and LVC were significantly higher on gadopentetate-enhanced images (P < .05). Gadopentetate might permit better delineation of infarcts, especially subendocardial infarcts. |
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Authors:
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Thomas Schlosser; Peter Hunold; Christoph U Herborn; Heidrun Lehmkuhl; Alexander Lind; Sandra Massing; Jörg Barkhausen |
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Publication Detail:
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Type: Comparative Study; Journal Article Date: 2005-07-29 |
Journal Detail:
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Title: Radiology Volume: 236 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 2005 Sep |
Date Detail:
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Created Date: 2005-08-24 Completed Date: 2005-10-04 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 1041-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Diagnostic and Interventional Radiology, University Hospital Essen, Hufelandstrasse 55, 45122 Essen, Germany. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Contrast Media Female Gadolinium DTPA / diagnostic use* Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging / methods* Male Meglumine / analogs & derivatives*, diagnostic use Middle Aged Myocardial Infarction / diagnosis* Organometallic Compounds / diagnostic use* Prospective Studies Statistics, Nonparametric |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 113662-23-0/gadobenic acid; 6284-40-8/Meglumine; 80529-93-7/Gadolinium DTPA |
| Comments/Corrections | |
Comment In:
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Radiology. 2006 Sep;240(3):914-5; author reply 915-6
[PMID:
16926338
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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