Document Detail

Myocardial fatty acid pattern in rats fed on an erucic acid enriched diet.
MedLine Citation:
PMID:  9528174     Owner:  NLM     Status:  MEDLINE    
Individual lipid classes and their fatty acid pattern in myocardium of rats fed on a diet containing 10% erucic acid ethyl ester (cis-13-docosenoic acid ethyl ester) were investigated and compared to rats fed on a normal diet. Two groups of rats were treated for 10 consecutive days with the erucic acid ethyl ester diet and the standard diet, respectively. After extracting total lipids from the myocardium of the rats, the individual lipid classes and the percentage of fatty acids in phospholipids, free fatty acids, diglycerides and triglycerides were measured. The data obtained demonstrate that the erucic acid ethyl ester diet induces a marked increase in free fatty acids and in triglycerides and marked differences in fatty acid pattern in triglycerides, free fatty acids and diglycerides, but only marginal differences in phospholipids, which seem to be carefully preserved as fundamental components of cell and mitochondria membranes.
A Marzo; S Curti; P Marzo; R Lisciani
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bollettino chimico farmaceutico     Volume:  136     ISSN:  0006-6648     ISO Abbreviation:  Boll Chim Farm     Publication Date:  1997 Nov 
Date Detail:
Created Date:  1998-04-23     Completed Date:  1998-04-23     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0372534     Medline TA:  Boll Chim Farm     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  651-6     Citation Subset:  IM    
Istituto di Farmacologia e Farmacognosia, Università La Sapienza, Rome, Italy.
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MeSH Terms
Chromatography, Gas
Erucic Acids / pharmacology*
Fatty Acids / metabolism*
Myocardium / metabolism*
Rats, Sprague-Dawley
Spectrophotometry, Ultraviolet
Reg. No./Substance:
0/Erucic Acids; 0/Fatty Acids

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