Document Detail

Myocardial depression in septic shock caused by meningococcal infection.
MedLine Citation:
PMID:  6439470     Owner:  NLM     Status:  MEDLINE    
Comparative hemodynamic measurements recorded in 19 cases of septic shock associated with Neisseria meningitidis bacteremia and in 20 shock cases associated with bacteremia due to other Gram-negative bacilli showed a significantly higher incidence of early myocardial depression in the cases with meningococcal infection. Echocardiographic, ECG, and serum enzyme (CK-MB isoenzyme) studies closely correlated with impaired myocardial contractility and development of cardiogenic shock in patients with meningococcal bacteremia. Autopsy of the heart from three patients who succumbed to shock confirmed the presence of myocarditis with intracellular Gram-negative diplococci. Our observations suggest that the onset of cardiac dysfunction precedes clinical manifestations of shock.
F Monsalve; L Rucabado; A Salvador; J Bonastre; J Cuñat; M Ruano
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Critical care medicine     Volume:  12     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:  1984 Dec 
Date Detail:
Created Date:  1985-02-05     Completed Date:  1985-02-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1021-3     Citation Subset:  AIM; IM    
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MeSH Terms
Cardiomyopathies / etiology*,  physiopathology
Meningitis, Meningococcal / complications*,  physiopathology
Myocardial Contraction
Neisseria meningitidis
Shock, Septic / etiology*,  physiopathology

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