Document Detail


Myocardial contrast echocardiography in the detection of coronary stenosis.
MedLine Citation:
PMID:  15158937     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The need for the capillary bed to maintain normal hydrostatic pressure results in capillary derecruitment distal to a stenosis during hyperemia. This pathophysiologic behavior is seen irrespective of the method by which coronary driving pressure is reduced. The functional consequences of the decrease in MBV are an increase in myocardial vascular resistance and a concomitant reduction in hyperemic MBF. These phenomena form the basis for the detection of CAD with MCE, which isa unique noninvasive tool that allows the separate assessment of both MBV and MBF velocity. Because of its excellent spatial and temporal resolution, portability, widespread availability,and relatively low cost, MCE should provide an attractive method for the noninvasive detection of CAD and for the quantification of stenosis severity.
Authors:
Khim Leng Tong; Kevin Wei
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Cardiology clinics     Volume:  22     ISSN:  0733-8651     ISO Abbreviation:  Cardiol Clin     Publication Date:  2004 May 
Date Detail:
Created Date:  2004-05-25     Completed Date:  2004-10-05     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8300331     Medline TA:  Cardiol Clin     Country:  United States    
Other Details:
Languages:  eng     Pagination:  233-51     Citation Subset:  IM    
Affiliation:
Cardiovascular Imaging Center, Box 800158, Cardiovascular Division, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
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MeSH Terms
Descriptor/Qualifier:
Blood Flow Velocity
Coronary Stenosis / physiopathology,  ultrasonography*
Coronary Vessels / physiology*,  physiopathology
Echocardiography* / methods
Humans
Hyperemia / physiopathology
Image Enhancement
Injections, Intravenous
Microbubbles
Microcirculation / physiopathology
Vascular Resistance
Vasodilation / physiology
Grant Support
ID/Acronym/Agency:
K08-HL03909/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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